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Researchers use CRISPR to speed up seek for HIV treatment

Researchers at UC San Francisco and the academically affiliated Gladstone Institutes have used a newly developed gene-editing system to search out gene mutations that make human immune cells immune to HIV an infection. The crew constructed a high-throughput cell-editing platform utilizing a variant of CRISPR/Cas9 know-how that allowed them to check how nicely scores of various genetic tweaks defended immune cells in opposition to HIV. The brand new system permits researchers to shortly modify the genetic code of freshly donated human immune cells and can hopefully speed up the search to lastly remedy HIV+ sufferers, the researchers stated. "That is a capability HIV researchers have wished for a very long time," stated postdoctoral researcher Judd F. Hultquist, PhD, one of many new paper's co-lead authors. "I hope this can take what appeared like an insurmountable activity a 12 months in the past and make it one thing every...